Welcome to the Structural Bioinformatcs Gateway at the NRBSC,
an NIH Research Resource

This site is devoted to disseminating the latest news on our research, development, and education efforts in structural bioinformatics.

Researchers led by Dr. Troy Wymore are involved in

• developing interfaces and databases to facilitate the construction of models for simulating enzyme reactions using hybrid Quantum Mechanical/Molecular Mechanical (QM/MM) potentials.
• developing state-of-the-art tutorials for constructing and simulating enzyme reactions using QM/MM potentials
• developing methods to advance template-based protein structure prediction methods.

• A separate core project funded by the Research Resource is developing methods and parameters for polarizable molecular mechanical force fields to be used in simulating biological systems and in particular ion channels. This project is led by Charles L. Brooks III at Scripps Research Institute.

Postdoctoral Opportunity in Bioinformatics
(read more)