NRBSC.org

Structural Bioinformatics

Projects in this area seek to utiliize the massive amounts of data from genomic and proteomic databases along with high-performance computing to determine protein structure and function.

Comparative Modeling

Comparative modeling at the NRBSC focuses on improving modeling protocols with novel algorithms, state-of-the-art scoring potentials, and refinement methods.

About CASP7

The seventh round of the Critical Assessment of Techniques for Protein Structure Prediction is a biannual experiment to evaluate computational methods of structure determination. Experimentalists solve protein structures by either X-Ray Crystallography or NMR without releasing the information to the public. Predictors have a short time period to try and build an accurate three-dimensional model from target sequence. Prediction methods are then evaluated against the experimentally solved structures. The experiment is succeeded by an addendum conference for discussing and critiquing prediction methods.